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Therefore, 13 C MRS has to be used after the exogenous infusion of a 13 C-labeled contrast agents (CA) [114, 125].The 19 F nucleus has a 100% natural abundance and its SNR is about 89% of 1 H per nucleus
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Although systemic inflammation is known to modulate iron metabolism, such as interleukin-6 (IL-6) stimulating hepcidin synthesis and subsequently downregulating FPN1, this has been observed primarily in hepatic tissues (95)
