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5 Thus, understanding the mechanisms responsible for both advantageous and detrimental effects of MTX is crucial for identifying new targets for treatment and achieving optimal therapeutic approaches for controlling immune-mediated and inflammatory diseases while reducing detrimental adverse events related to toxicity
DallOglio F, Puviani M, Milani M, Micali G

Pyruvate embodies antioxidant properties due to its -keto carboxylate structure which enables it to directly and non-enzymatically neutralize peroxides and peroxynitrites 45

Two-stage culture is another commonly used method for strain screening

This suggests that MZB and FoB depend on a different redox state and that the loss of GSH in FoB may induce MZB-like properties

(2021) 16:e0248691
