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The amino acid's role extends beyond simple neurotransmitter production to include thyroid hormone synthesis, where it serves as a backbone component for thyroxine (T4) and triiodothyronine (T3) formation

Considering that meldonium primarily impacts glycolysis and metabolic pathways [27], its mechanism of action in treating CIRI may involve promoting glucose use in the brain [10, 17, 26, 28]

However, these genetic associations are inconsistent as studies typically have quality-control issues (56)

The peak levels rose in a dose-dependent manner within approximately 2.5 hours, and the pharmacological effects persisted for about six hours

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Thanks to its blend of amino acids (Citrulline, Beta-Alanine, Agm