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Description
In the Gdap1 / mice, there is no change in M2 microglia (CD206+ve expression) typically associated with anti-inflammatory cytokines, debris clearance, and tissue repair
Age-dependent accumulation of oligomeric SNCA/-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA)

On the other hand, depletion of GSH increases the toxicity of alkylating agents both in vivo and in vitro 43

Khoshsirat, S., et al

92 s -Adenosyl-l-homocysteine can be used for pyrimidine synthesis or converted into homocysteine, which can be re-methylated to methionine or enter the trans-sulphuration pathway to generate cysteine, through CBS and CSE

Staunton, et al
