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Assessment of the combined effects of chromium and benzene on the rat neuroendocrine and immune systems
The high local potency combined with short half-life offers theoretical advantages over systemic analogs: targeted effects with reduced whole-body exposure and associated risks

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A recent meta-analysis including five studies evaluating NAC and 574 patients with depression (291 randomized to NAC and 283 to placebo) with a follow-up of 1224 weeks revealed significantly greater improvements in depressive symptoms (MADRS) and functionality with NAC than with placebo [143]
