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295 In addition, high expression of TLR4 can increase H 2 O 2 production in the colonic mucosa of UC mice, induce redox activity in the mucosa, exacerbate oxidative stress, and promote the disease progression of UC

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van der Houwen, L

Histopathology of Preclinical Toxicity Studies: Interpretation and Relevance in Drug Safety Evaluation

To promote in vivo recombination in yeast, the genes were PCR-amplified to introduce specific overhangs of 4055 bp to the linearized vector using iProof high-fidelity polymerase (Bio-Rad, 1725301) following the manufacturers specifications