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These situations warrant pausing: Severe, persistent vomiting that prevents adequate hydration for more than 48 hours

Sawka et al

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Eraj S, Jomaa M, Rock CD, Mohamed ASR, Hutcheson KA, Sturgis EM, Lu C, Morrison WH, Rosenthal DI , Frank SJ, Garden AS, Fuller CD, Gunn GB
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Sleep was technically adequate, but no longer what it was at 35