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Review supplementation If elevated B12 results from excessive supplementation: Discontinue or reduce high-dose supplements unless medically indicated For patients receiving therapeutic B12 injections for confirmed deficiency, continue treatment as prescribedelevated levels are expected after replacement therapy and do not indicate toxicity Review with GP to ensure supplementation remains appropriate 3

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2015;7:a006080 Galluzzi L, Vitale I, Aaronson SA, Abrams JM, Adam D, Agostinis P, et al

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2021;7:e06117