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Ping Dou Q Dithiocarbamate-Based Coordination Compounds as Potent Proteasome Inhibitors in Human Cancer Cells

Sikiric, P., Seiwerth, S., Rucman, R., Kolenc, D., Vuletic, L

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However, this normalized state is not achieved in individuals with weak HLA-II haplotypes against EBV, presenting an impaired CD4 T-cell function and, therefore, a deficient CD8 T-cell cytotoxic response

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They are essential for initiating and regulating immune responses