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Similarly assessing combination therapies, an open label, single arm study delivered by Negrao et al

You have a lot of them when your immune system is working against your tissues
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Gandomi H, Abbaszadeh S, Rahimikia E, Shariatifar N

Where possible, avoid suddenly reducing the B 12 dose or injection frequency, as too rapid dose reduction may worsen symptoms or lead to symptom recurrence.26 Instead, gradually increase the interval between B 12 injections over the course of several months while monitoring symptoms

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