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However, several findings from studies performed in Saccharomyces cerevisiae suggest that the role of PPP in oxidative stress response goes beyond NADPH generation only

This may mediate activation of perivascular Ms, microglia, and astrocytes, and initiate further immune responses within the brain parenchyma, suggesting neuroinflammation can be triggered by signaling from the periphery, without primary injury or disease originating within the CNS

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Eur J dermatology: EJD

Oct 2020;130:110714

J Immunol (2020) 204(1 Supplement):73.9