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Similar content being viewed by others Introduction Ferroptosis is an iron-dependent form of regulated cell death driven by the uncontrolled accumulation of lipid peroxides 1

[DOI] [PMC free article] [PubMed] [Google Scholar] 331.Traverso N., Ricciarelli R., Nitti M., Marengo B., Furfaro A.L., Pronzato M.A., Marinari U.M., Domenicotti C

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It upregulates the expression of early growth response protein 1 (EGR-1), a transcription factor that controls over 30 downstream genes involved in cytokine production, growth factor signaling, and extracellular matrix remodeling