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Structurally, the mechanical component is formed by intestinal epithelial cells and vascular endothelial cells joined by tight junctions, adherens junctions, and cadherin proteins, thereby ensuring selective nutrient transport

[DOI] [PubMed] [Google Scholar] 179.Wit JM

Their colonization within the human body stems from intricate interactions with multiple facets of host physiology and metabolism, reflecting a finely tuned relationship

The physiological role of Treg cells is to maintain immune tolerance by suppressing effector T-cell activity and preventing inappropriate immune responses

Most evidence supporting the blend rationale comes from animal models and pharmacological modeling

10.1016/j.plipres.2008.10.002
