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The mTOR pathway activates NLRP3 by driving anabolic processes

doi:10.1124/jpet.105.085431

These findings demonstrate a stress-intensity-dependent aggravation of anxiety-like behavior and further reveal that KI mice possess heightened vulnerability to cumulative social stress exposure

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The study was conducted in accordance with the Declaration of Helsinki, and the protocol was approved by the Independent Bioethics Commission for Research at Medical University of Gdansk Ethics (NKBBN/354-304/2015)

Representative gating for all experiments can be found in Supplementary Fig