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They comprise diverse subpopulations characterized by their ontogeny and polarization state ( During the resolution of inflammation, macrophages accumulate glutamine from the extracellular environment or through the engulfment of apoptotic cells and break it down into the TCA cycle intermediate -ketoglutarate ( Recent studies suggest that crosstalk between macrophages and other immune cells such as mast cells may affect their metabolic fates and enhance functional outcomes during immune activity

[DOI] [PubMed] [Google Scholar] 153.Sengupta P., Dutta S., Liew F.F., Dhawan V., Das B., Mottola F., Slama P., Rocco L., Roychoudhury S

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[179] Lack of copper can manifest as neutropenia, microcytic anemia, growth disturbances or slowing of erythropoiesis

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Cellular and Molecular Life Sciences, 57(7), 1050-1093