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More severe disease is associated with progressive destruction and loss of elastin, smooth muscle, mucous glands and cartilage
Glial reactivity or CNS inflammation could also retroact on the metabolism in ME/CFS since inflammatory stimulation or broadly restricted perfusion may cause mitochondrial dysfunction
doi: 10.1016/j.redox.2019.101154 100 RenX.ZouL.ZhangX.BrancoV.WangJ.CarvalhoC.et al
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Overcoming NOTCH1-Driven Chemoresistance in T-Cell Acute Lymphoblastic Leukemia Via Metabolic Intervention with Oxphos Inhibitor
