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Interactions between genetic and environmental factors affecting mother before and during pregnancy, e.g., chemicals (arsenate, mercury, lead, polychlorinated biphenyls, toluene, and pesticides), perinatal injuries, infections during pregnancy, hypoxia, preterm delivery, and intensive antibiotic therapies during pregnancy disturbing embryogenesis, are thought to significantly impact ASD occurrence [2]

AMPK sequence: siRNA1: 5-GCACGAGUUGACUGGACAUTT, AUGUCCAGUCAACUCGUGCTT-3, siRNA2: 5-CCUUUCUGGUGUGGACUAUTT, AUAGUCCACACCAGAAAGGTT-3, siRNA3: 5-CCAUUCUUGGUUGCCGAAATT, UUUCGGCAACCAAGAAUGGTT-3

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Razzaque, Lake Erie College of Osteopathic Medicine, United States Reviewed by Naseh Pahlavani, Torbat Heydarieh University of Medical Sciences, Iran

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Hagen TM, Liu J, Lykkesfeldt J, Wehr CM, Ingersoll RT, Vinarsky V, Bartholomew JC, Ames BN: Feeding acetyl-L-carnitine and lipoic acid to old rats significantly improves metabolic function while decreasing oxidative stress
