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Louis Aronne (an obesity specialist) famously noted, We will need many different treatments if we are going to manage obesity successfully, in much the same way we have many treatments for diabetes and hypertension

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Reduced cortisol implies less suppression of GnRH neurons and less disturbance in LH and FSH release

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B12 is also involved in many of these processes, but it works alongside folate as a coenzyme in these processes: both vitamins are required for normal function