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Taken together, these findings suggest that NAC can cross the intact BBB but then is rapidly eliminated via OAT1 and OAT3 (and perhaps other probenecid-inhibitable membrane transporters)

doi: 10.1159/000338637 50 WiersingaWMDuntasLFadeyevVNygaardBVanderpumpMP
Les effets sont rels." Visuel produit L'essentiel en un coup d'il

[DOI] [PMC free article] [PubMed] 111.Hoyo C, Schildkraut JM, Murphy SK, Chow WH, Vaughan TL, Risch H, et al

The current branded form, Egrifta WR, was FDA-approved in March 2025 and became available in September 2025

doi:10.1074/jbc.M800677200
