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Indeed, it was recently reported that treatment of cells with H 2 O 2 , which can lower GSH levels, leads to increased expression of NRF2 target genes in a KEAP1-independent mechanism 69

[103] Yamada N, Matsushima-Nishiwaki R, Masue A, Taguchi K, Kozawa O
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Some of the spurious peaks that appeared in the spectra might be due to the presence of non-target compounds in the samples, such as fat, vitamins, lactose, etc

doi: 10.2337/dc22-1744 94

The internal control used was 18 S
