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Overall, the data favor a role for diets rich in long-chain omega-3 fatty acids in slowing cognitive decline, but larger trials with longer intervention periods may be necessary to see a consistent beneficial effect of omega-3 supplementation in older individuals with normal or declining cognitive functions

Liver-specific loss of long chain acyl-CoA synthetase-1 decreases triacylglycerol synthesis and beta-oxidation and alters phospholipid fatty acid composition

The impact of this cellular energy crisis extends far beyond skeletal muscle fatigue

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American Journal of Medical Genetics Part C: Seminars in Medical Genetics

Surg Clin North Am