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The delivery concept is plausible, and small human studies support biological delivery from tested formulations

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[DOI] [PMC free article] [PubMed] 200.Wilson S, Chia SK

For example, during senescence, plants produce large amounts of serotonin, and the synthetic pathway involves the metabolism of serotonin to 5-methoxytryptamine via ASMT/COMT

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Two studies from the early 1980s suggest that dietary concentrations of 2.03.0 ppm would be required to meet tissue needs and to increase reproductive performance (Easter et al., 1983