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doi: 10.3389/fendo.2013.00066 27 AndersonSMShahNEvansWSPatrieJTBowersCYVeldhuisJD

When NF-kB interacts with IkB in the cytoplasm, it is unable to enter the nucleus and bind to the promotor region of proinflammatory genes

This was consistent with many natural compounds (Wang et al., 2020)

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A has also been demonstrated to activate microglia and result in inflammatory damages [11]
