glutathione mitochondrial density Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells Glutathione Depletion in Mitochondrial Diseases

The overexpression of this enzyme in the astrocytes of glial fibrillary acidic protein-heme oxygenase-1 (GFAP-HMOX1) transgenic mice resulted in increased subcortical oxidative imbalance with the induction of mitochondrial damage and autophagy, augmented dopamine and serotonin levels in the basal ganglia, and reduced dopamine 1 receptor (D1) in the nucleus accumbens, and enzyme overexpression caused degeneration of axons in the hippocampus and hyperkinetic behavior [44]

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PMID: 40669021