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In this Review, the authors consider advances in therapeutic strategies and neurosurgical procedures, including acute care bundles, that promise a new era of interventions.

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This study also suggests that it is important to identify ASD/MD children as they may respond differently to specific treatments because of their specific metabolic profile.

We identify a set of genes upregulated by bb and demonstrate that the enzymes encoded by the induced bb utilization ( bbu ) gene cluster convert bb to TMA