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Selective inhibition of soluble TNF using XPro1595 relieves pain and attenuates cerulein-induced pathology in mice

Two of these peptide hybrids (phybrids) had a C-terminally truncated Exenatide, which was covalently linked to the N-terminus of an amylin analogue (Davalintide) through either a repeat -ala--ala dipeptide, or through triple-glycine linear repeat

doi: ^ Iizuka K., Takao K., Yabe D

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The precise mechanisms underlying this resistance remain unclear