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American Journal of Physiology

when cells are exposed to this stimulus, the NRF2Keap1 complex is disrupted, allowing NRF2 to escape and resulting in Keap1-mediated degradation

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Furthermore, Parthimos et al., found that post training supplementation with l-carnitine improved the total antioxidant status, which was otherwise observed in basketball players in the absence of supplementation [74]

Carnitine can also exert anti-inflammatory effects by inhibiting the polarization of M1 macrophages and reducing the activity of Th17 cells and other proinflammatory cell populations [50, 51]