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JeonPLimongiRFordSDBrancoCMackinleyMGuptaMet al

ORR is defined as the proportion of patients with a best response of complete response (CR) or partial response (PR) by the RECIST 1.1 criteria recorded between Day 1 of the study and the date of objectively documented progression per RECIST 1.1 or the date of subsequent anti-cancer therapy, whichever occurred first

doi: 10.1080/10177833.2010.11790631

Animal studies using the gold-standard euglycemic clamp technique confirmed that even chronic AOD-9604 treatment produced no adverse effects on insulin sensitivity, despite significant fat loss occurring