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The glutathione (GSH) redox system plays a central role in maintaining cellular homeostasis, but its dysregulation in cancer contributes to tumor progression, therapy resistance, and metabolic adaptation

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The most extremely unfavourable outcome of pregnancy is the death of the mother and newborn

Metabolomics and lipidomics have enabled the identification of metabolites (such as lipids, amino acids and bile acids) and metabolic pathways that modulate insulin sensitivity both directly and indirectly

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In particular, GSDME-deficiency significantly attenuated the hippocampal atrophy and changed levels of DAM markers in GCLC-KO mice