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H 2 O 2 output rises with high secretory load and activation of the unfolded protein response (UPR^ER) and is further modulated by Ca fluxes as well as mono-oxygenase systems such as cytochrome P450 and cytochrome b reductase (Roscoe and Sevier 2020)

Subsequently, 180 l fresh culture medium and 20 l of samples (0.05858000 M in sterile water) were added per well and incubated for 24, 48 and 72 hours