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While these studies are groundbreaking for patients seeking answers, they are primarily observational
However, it proved ineffective and was discontinued for this use

This property makes the agents potential sensitizers, chemicals that can cause people who are regularly exposed to them to develop an allergy

Medications to treat this, like levothyroxine, can cause irregular, late, or missed periods
ClinicalTrials.gov has assigned the study number NCT03806478 to the APH-1105 study, which is a Phase 2 clinical investigation that was launched in 2019

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