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Oakley AJ, Lo Bello M, Mazzetti AP, Federici G and Parker MW

Prevalence of orthostatic hypotension in Parkinsons disease: a systematic review and meta-analysis

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A randomized, double-blind, controlled phase II trial in advanced renal cell carcinoma (RCC) demonstrated synergistic anticancer effects with the combination of the glutaminase inhibitor telaglenastat (CB-839) and the mTOR inhibitor everolimus (TelaE), which was well tolerated by patients previously treated with TKIs

[DOI] [PMC free article] [PubMed] [Google Scholar] 573.Prasad AS, Bao B, Beck FW, Kucuk O, Sarkar FH

Nevertheless, subgroup analyses revealed that patients with RAS mutation had a significantly longer progression-free survival following vitamin C administration (9.2 versus 7.8 months