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10.1093/toxsci/kfy159 4 BhargavaV.SinghK.MeenaP.SanyalR

doi: 10.1113/ep085207 211

S.ChanC

The 57 CYP genes identified from the human genome project gave new insight into the extent of CYP isoforms, with many of these enzymes covering a large range of functions, although the role of some isoforms remains unknown (Ingelmansundberg, 2005)

This means that ferroptosis can induce other kinds of cell death, and/or it plays a minor effect in cell death, or we use inhibitors after the reversible point and once this threshold is exceeded, ferroptosis will be irreversible Recently, we also found that ferroptosis is vital for tumor immunity such as macrophage phagocytosis (71) and T cell killing (115) but the crosstalk between ferroptosis and the glioma immunosuppressive microenvironment is not clear
VCH Verlagsgesellschaft, Weinheim, Deerfield Beach
