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As you get older, your body naturally produces less NAD+
REDEFINE 2 showed 13.7% in T2D patients at 68 weeks

Toutefois on estime que jusqu' 18% des nphropathies terminales pourraient tre dues la prise d'analgsiques et jusqu' 5% avoir une origine toxique quelconque

Anyone with significant medical conditions, anyone pregnant or breastfeeding, and anyone on multiple medications needs a careful review first not because problems are expected, but because limited human data means we don't assume

intermittent treatment with senolytics have conclusively reduced senescent cell burden in peripheral tissues (fat, lung, kidney, pancreas, cartilage, and muscle), improved pathologies in these tissues, and extended healthspan and lifespan (45, 46, 100-103)

Women in rural areas, women without specialist access, and women whose prescribers are not comfortable initiating HRT face disproportionate barriers
