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In a 2013 study, 15 the GSH precursor N -acetyl cysteine (NAC) was administered as a single 60-min intravenous infusion (150 mg/kg) to individuals with PD and healthy controls

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Therefore, successful clinical translation of macrophage polarization therapies requires the development of spatiotemporally controllable delivery systems, the establishment of dynamic biomarker profiles, and a deeper investigation into disease-specific polarization mechanisms, with the ultimate goal of achieving precise immune remodeling

J Occup Environ Med 54 , 11571162 (2012)

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