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Younger people can also become deficient, particularly if they don't eat a balanced, nutrient-rich diet

The researchers found that Vitamin C administration caused a rapid, statistically significant reduction in serum histamine levels, proving its clinical utility in states of pathological histamine excess like MCAS

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J Biol Chem 257(23):1421714225 Yang J, Shen J (2007) Relayed (13)C magnetization transfer

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It recruits CRL4 CRBN to ENL through an extended interface of protein-protein and protein-ligand contacts, but only after pre-forming the ENL:dHTC1 complex