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Description

Recently, a class of proteins known as SIRTS or sirtuins (also known as silent information regulator 2 [Sir2]-related enzymes) has been implicated in an effect of CR on lifespan extension and the prevention of comorbidities associated with obesity [233, 234]

Modulation of Inflammatory Cytokines: KPV acts as a potent anti-inflammatory tripeptide by inhibiting nuclear factor kappa-B activation and reducing production of TNF-alpha IL-beta, and IL-6

This combination enhances its ability to stimulate cellular repair processes and promote collagen production

Structural visualization, image processing, and analysis of docking results were performed using PyMOL 2.5.2

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