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PMCID: PMC8397910

During exercise, the muscle signals its energy requirements to the liver by changing the concentration of acylcarnitine in the blood, and the liver adjusts its metabolic activity to increase the synthesis and release of energy substances [223, 224], support muscle contraction and meet the energy demands of exercise [225, 226]

Iwanaga J, Shiromoto K, Kato T, Tanaka T, Ibaragi S, Tubbs RS

Tanaka, L

Clinical research of L-carnitine treatment on sixty-two patients with chronic congestive heart failure

In fact, L-carnitine can improve the imbalance between oxidant (ROS) and antioxidant species caused by busulfan, and decrease oxidative stress through ROS reduction and increase of antioxidants such as GSH and SOD