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GHS-R deletion decreases dopaminergic activity in the ventral tegmental area (VTA) by down-regulating DAT, but increases dopaminergic activity by up-regulating the expression of both dopamine synthesis enzyme (TH) and DAT in SN of HFD-fed neuronal-specific GHS-R knockout mice 9

Additionally, research on Danzhi-Xiaoyao-San has revealed how it affects neurotransmitter levels by altering the metabolites of the intestinal microbiota, offering new insights for developing future therapeutic drugs [600]

The reducing effects of pyrogallol-phloroglucinol-6,6-bieckol on high-fat diet-induced pyroptosis in endothelial and vascular smooth muscle cells of mice aortas

del Bo'CMarinoMMartiniDTucciMCiappellanoSRisoPet al

doi:10.1111/j.1432-1033.1997.00273.x

Sagging skin, age spots, superficial fine lines and wrinkles, and pigmentation are among common signs of aging
