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While GSH has controlling properties, it is dependent upon its amplifying enzymes, such as GSH peroxidases, S-transferases, and GSH reductases

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Also, region-specific intraneuronal iron load was assessed by T2* MRI and was shown to decrease in the active-treatment groups, but it did not correlate with significant clinical improvement in terms of changes in the UPDRS scores (Martin-Bastida et al

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These effects were also demonstrated in clinical trials where flavanols improved insulin sensitivity and decreased HbA1c