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Cell lines harboring a PIK3CA -activating mutation or a PTEN -inactivating mutation showed ferroptosis resistance mediated via activation of the PI3K/AKT/mTOR pathway, which further upregulates SREBP1 101

Instead of oral glutathione, consider N-acetylcysteine (600mg twice daily), which provides the cysteine substrate for hepatic glutathione synthesis and has documented hepatoprotective effects in acetaminophen toxicity and non-alcoholic fatty liver disease

One pitfall of this meta-analysis is that most of the incorporated RCTs are single-centered trials, which have intrinsic single-center bias

Symptoms like severe dizziness, trouble breathing, hives, and swelling of the face, lips, tongue, or throat require urgent care

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