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Although LDH is primarily used clinically as a prognostic biomarker reflecting tumor burden, growing evidence suggests that it also plays functional roles in tumorigenesis and progression (41)

Tracer amino acids for metabolic and structural studies

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Pediatr Diabetes 20(7):849-60 2019 PMC6786916 Mokhlesi B, Temple KA, Tjaden AH, Edelstein SL, Nadeau KJ, Hannon TS, Manchanda S, Sam S, Barengolts E, Utzschneider KM, Ehrmann DA, Van Cauter E, RISE Consortium

The pathophysiological process begins with reduced glucose intake as a result of a fasting state or increased energy needs from a catabolic state (infection, stress, fever, etc...) not sufficiently provided for by caloric intake

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