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Thus, because of the expected defect in NADPH production by the oxidative branch of the PPP due to G6PD deficiency (Figure 5), G6PD-deficient RBCs have storage-induced decreases in GSH, hexose sugar alcohol, and DHN, which are produced by NADPH-consuming reactions (Figure 7)

Full growth hormone administration can stimulate cortisol production through various mechanisms, and elevated cortisol is well-documented to increase appetite, particularly for high-calorie comfort foods, and promote abdominal fat accumulation

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doi: 10.1016/j.jbc.2022.102183, 129

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