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DMSO consistently showed effects different from the water control both at the mRNA and protein level of estrogenic target genes/proteins

Chen, Thomas C.Neuro-Oncology (Cary, NC, United States) (2021), 23 (10), 1656-1667CODEN: NEURJR

This product is supplied strictly for research purposes only and is not intended for human consumption

Mechanism of PRP in Osteoarthritis PRP contains growth factors and cytokines that promote cartilage repair and modulate inflammation, including: Platelet-derived growth factor (PDGF): Stimulates chondrocyte proliferation and matrix synthesis Transforming growth factor-beta (TGF-): Encourages cartilage regeneration and reduces catabolic activity Vascular endothelial growth factor (VEGF): Enhances microcirculation to support healing Interleukin-1 receptor antagonist (IL-1Ra): Suppresses pro-inflammatory cytokines that degrade cartilage These biological effects differentiate PRP from corticosteroids , which primarily suppress symptoms but accelerate cartilage degradation with repeated use (PMID: 30404447)