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In pathologic conditions, the loss of HS disrupts the charge selectivity of the glomerular filtration barrier, which increases the filtration of proteins and leads to proteinuria (97)

[DOI] [PubMed] [Google Scholar] 83.Bayer IM, Caniggia I, Adamson LS, Langille LB

MOTS-C A mitochondrial peptide known for its ability to influence cellular energy regulation

This route provides steady absorption over 4-6 hours, longer than intramuscular injection but with less discomfort and easier self-administration