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Critically, VD and VE also reinforce BBB integrity by up-regulating tight junction proteins (claudin-5, ZO-1) and suppressing MMP-9, disrupting the albumin-TGF-driven hyperexcitability cycle

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It may also cause allergic reactions in some individuals

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Many of the studies on oxalates focus on kidney stone formation, and these studies provide a clear picture of the interaction between oxalate homeostasis, kidney function, and calcium levels

doi:10.1007/s00109-016-1488-y