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N Engl J Med 364(6):501513 Raymundo DP, Doultsinos D, Guillory X, Carlesso A, Eriksson LA, Chevet E (2020) Pharmacological targeting of IRE1 in cancer

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For patients with a single cartilage lesion greater than 8 cm 2 , multiple lesions, or joint wide cartilage degeneration, whole or hemi-joint tissue engineering is an attractive alternative to metal/plastic joint replacement

doi:10.1016/j.amjcard.2020.10.043 Masson W, Lobo M, Molinero G, Masson G, Lavalle-Cobo A