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Its mechanisms are broad

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Nrf2 depletion in macrophages leads to increased foam cell formation, increases the M1 inflammatory phenotype with enhanced expression of pro-inflammatory monocyte chemoattractant protein-1 and interleukin-6, and aggravates atherosclerosis (244, 245)

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Understanding Tesofensine and GLP-1 Agonists Tesofensine, classified as a novel triple monoamine reuptake inhibitor, presents a unique mechanism of action in the realm of weight loss medications