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Other studies have shown that the coordinated modulation of STAT6 and p38 MAPK exhibited potential effects on the induction of IL4 and IL13 and that p38 MAPK could directly regulate the activity of the transactivation domain of STAT6 [47,48,49]

Among these mimics, high-molecular-weight (MW) molecules and fibulin-5 have been reported as promising early-disease stage therapeutics

The truth sits between the extremes: MTHFR is a gene-nutrient interaction

Wang Y, Han D, Zhou T et al (2020) Melatonin ameliorates aortic valve calcification via the regulation of circular RNA CircRIC3/miR-204-5p/DPP4 signaling in valvular interstitial cells

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Zhou, Y., et al., Disease burden of liver cancer in China from 1997 to 2016: an observational study based on the Global Burden of Diseases