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Regarding the mechanisms by which TTh may worsen OSA, anatomic TTh-induced airway changes and altered sleep stage architecture have been largely refuted

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For example, METTL3 promotes ferroptosis through m6A methylation of HMGB1, leading to cartilage degradation and pain in OA

[DOI] [PubMed] [Google Scholar] 77.Davis M., Myers K.M

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